C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12Q 1/04 (2006.01) C12Q 1/18 (2006.01) C12Q 1/48 (2006.01) G01N 33/573 (2006.01) C12N 15/52 (2006.01)
Patent
CA 2419461
The present invention features methods for the identification of compounds and compositions useful as antibiotics and antibacterial agents. In particular, the invention features methods for the identification of modulators of a previously unidentified target protein, termed CoaX. High-throughput assay systems are featured as well as assay kits for the identification of CoaX modulators. Also featured are coaX nucleic acid molecules and purified CoaX proteins, as well as recombinant vectors and microorganisms including the gene, coaX.
L'invention concerne des procédés relatifs à l'identification de composés et de compositions utiles comme antibiotiques et agents antibactériens. L'invention concerne en particulier des procédés relatifs à l'identification de modulateurs d'une protéine cible précédemment non identifiée, portant l'appellation CoaX. L'invention concerne en outre des systèmes d'essai à rendement élevé et des kits d'essai pour l'identification des modulateurs CoaX. L'invention concerne enfin des molécules d'acides nucléiques coaX et des protéines CoaX purifiées, ainsi que des vecteurs de recombinaison et des micro-organismes renfermant le gène coaX.
Patterson Thomas A.
Yocum R. Rogers
Borden Ladner Gervais Llp
Omnigene Bioproducts Inc.
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