Microorganisms and methods for production of 1,2-propanediol...

Details Microorganisms and methods for production of 1,2-propanediol... Microorganisms and methods for production of 1,2-propanediol...

C - Chemistry, Metallurgy

12

P

C12P 7/02 (2006.01) C12N 9/02 (2006.01) C12N 15/09 (2006.01) C12P 7/26 (2006.01)

Patent

CA 2688450

The present invention concerns a modified microorganism with an increased methylglyoxal reductase activity, and its use for the preparation of 1,2-propanediol and/or acetol. In particular this increased methylglyoxal reductase activity is obtained by increasing the expression of specific genes from microorganisms. This invention is also related to a method for producing 1,2-propanediol and/or acetol by fermentation of a microorganism having an increased methylglyoxal reductase activity.

L'invention concerne un micro-organisme modifié possédant une activité augmentée de méthylglyoxal réductase, ainsi que son utilisation pour préparer 1,2-propanediol et/ou acétol. On obtient, plus particulièrement, cette activité augmentée de méthylglyoxal réductase par augmentation de l'expression de gènes spécifiques provenant de micro-organismes. L'invention concerne également un procédé servant à produire 1,2-propanediol et/ou acétol par fermentation d'un micro-organisme possédant une activité augmentée de méthyloxal réductase.

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