Microorganisms for imaging and/or treatment of tumors

Details Microorganisms for imaging and/or treatment of tumors Microorganisms for imaging and/or treatment of tumors

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 35/76 (2006.01) A61K 39/285 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/02 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/863 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2690627

Modified viruses encoding transporter proteins and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses also can be used in diagnostic methods, such detection and imaging of tumors. The viruses also can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents.

L'invention porte sur des virus modifiés codant pour des protéines de transporteur et sur des procédés pour préparer les virus modifiés. L'invention porte également sur des vaccins qui contiennent les virus. Les virus peuvent également être utilisés dans des procédés de diagnostic, tels que la détection et l'imagerie de tumeurs. Les virus peuvent également être utilisés dans des procédés de traitement de maladies, tels que des troubles prolifératifs et inflammatoires, comprenant des agents antitumoraux.

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