C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/20 (2006.01)
Patent
CA 2710666
The invention relates to microorganisms for the treatment of food allergies, specifically coeliac disease, as well as to methods for the selection thereof. The action mechanisms of said microorganisms include: (i) the regulation of the innate and adaptive immunological responses; (ii) the reduction of the concentration of toxic gluten peptide epitopes in the intestinal lumen; (iii) the strengthening of the barrier defence function against harmful antigens and bacteria; and (iv) the provision of enzymatic activities that promote digestion.
La presente invención aporta microorganismos para el tratamiento de alergias alimentarias, más concretamente la enfermedad celiaca, así como métodos para su sección. Sus mecanismos de acción incluyen: (i) la regulación de la respuesta inmunológica innata y adaptativa; (ii) la reducción de la concentración de epítopos tóxicos en la luz intestinal; (iii) el fortalecimiento de la función barrera defensiva frente a bacterias y antígenos perjudiciales, y (iv) el aporte de actividades enzimáticas que favorecen la digestión.
de Palma Giada
Medina Marcela Susana
Nadal Gimenez Inmaculada
Sanchez Sanchez Ester
Sanz Herranz Yolanda
Consejo Superior de Investigaciones Cientificas
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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