Microorganisms for the production of 1,4-butanediol

Details Microorganisms for the production of 1,4-butanediol Microorganisms for the production of 1,4-butanediol

C - Chemistry, Metallurgy

12

N

C12N 1/21 (2006.01) C12N 15/00 (2006.01) C12N 15/53 (2006.01) C12N 15/60 (2006.01) C12N 15/61 (2006.01) C12P 7/18 (2006.01)

Patent

CA 2735883

The invention provides non- naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO. The invention additionally provides methods of using such microbial organisms to produce BDO.

La présente invention concerne des organismes microbiens d'origine non naturelle capables de produire du 1,4-butanediol (BDO) grâce à au moins un acide nucléique exogène codant une enzyme de la voie de synthèse du BDO exprimée en quantité suffisante pour produire du BDO. L'invention concerne en outre des procédés d'utilisation de ces organismes microbiens pour produire du BDO.

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