Microparticle drug delivery system

Details Microparticle drug delivery system Microparticle drug delivery system

A - Human Necessities

61

K

167/159

A61K 9/50 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 31/56 (2006.01) A61K 39/00 (2006.01) C07K 16/00 (2006.01) C12N 11/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1143289

ABSTRACT OF THE DISCLOSURE Antibody or antigen containing microparticles for the active or passive immunization of the internal femal reproduc- tive organs, comprising microparticles of an antigen or anti- body incorporated in a matrix material which is biocompatible and biologically degradable, said microparticles capable of being transported after deposition in the vagina by the natural transport mechanism of the internal female reproductive organs across the cervix into the uterus. A contraceptive composition capable of being directly delivered to the uterus and fallopian tubes comprising microparticles of a biodegardable and bio- compatible matrix material having sperm surrogate activity and containing a contraceptive agent and a transport inducing hormone which when released stimulates the transport of the microparticles across the cervix into the uterus and fallopian tubes with the proviso that the contraceptive agent and hormone are different when the contraceptive agent is a hormone.

336744

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