Microparticle inhalation formulations

A - Human Necessities – 61 – K

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A61K 9/12 (2006.01) A61K 9/14 (2006.01) A61K 47/24 (2006.01)

Patent

CA 2319100

Aerosol formulations containing stabilized particles of drug microparticles with a mean size range of 0.1 to 10 microns coated with a membrane-forming amphiphatic lipid and dispersed in 1,1,1,2- tetrafluoroethane (HFA 134a) of 1,1,1,2,3,3,3-heptafluoropropane (HFA 227) propellant.

L'invention concerne des formulations d'aérosol contenant des particules stabilisées de microparticules médicamenteuses avec une taille moyenne comprise entre 0,1 et 10 microns, recouvertes d'un lipide amphiphatique formant membrane, et dispersées dans un gaz propulseur de 1,1,1,2-tétrafluoroéthane (HFA 134a) de 1,1,1,2,3,3,3,-heptafluoropropane (HFA 227).

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