A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 9/16 (2006.01) A61K 9/66 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) A61K 39/12 (2006.01) A61K 39/205 (2006.01) A61K 39/29 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2276066
A preparation of microparticles made up of a polymeric matrix, a nucleic acid expression vector, and a lipid. The polymeric matrix includes one or more synthetic polymers having a solubility in water of less than about 1 mg/l. At least 90% of the microparticles have a diameter less than about 100 microns. The nucleic acid is either RNA, at least 50% of which is in the form of closed circles, or circular DNA plasmid molecules, at least 50% of which are supercoiled.
Hedley Mary Lynne
Lunsford Lynn B.
Putnam David
Eisai Inc.
Smart & Biggar
Zycos Inc.
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