Microparticles useful as ultrasonic contrast agents and for...

A - Human Necessities – 61 – K

Patent

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A61K 9/50 (2006.01) A61K 41/00 (2006.01) A61K 47/48 (2006.01) A61K 49/04 (2006.01) A61K 49/22 (2006.01)

Patent

CA 2289088

Microparticles are provided comprising a shell of an outer layer of a biologically compatible material and an inner layer of biodegradable polymer. The core of the microparticles contain a gas, liquid or solid for use in drug delivery or as a contrast agent for ultrasonic contrast imaging. The microparticles are capable of passing through the capillary systems of a subject.

L'invention porte sur des microparticules comportant une enveloppe faite d'une couche extérieure d'un matériau biocompatible, une couche intérieure d'un matériau biodégradable, ainsi qu'un noyau gazeux, liquide ou solide, et qui servent à l'administration de médicaments ou d'agents de contraste pour l'imagerie par ultrasons. Lesdites microparticules peuvent circuler dans les systèmes capillaires d'un patient.

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