Microparticulated vaccines for the oral or nasal vaccination...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/20 (2006.01) A61K 9/16 (2006.01) A61K 9/28 (2006.01) A61K 47/36 (2006.01) A61K 47/48 (2006.01) A61P 31/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2756883

The invention relates to a composition and a method for manufacturing semi-dry or dry particles containing a mu-coadhesive polymer and a bioactive agent such as, but not limited to, an Immunogenic Substance (e.g., a vaccine), that allows the oral or nasal administration and delivery of the bioactive agent essentially unaltered to mucosal surfaces in the animal, including an aquatic animal.

La présente invention concerne une composition et un procédé de fabrication de particules déshydratées ou semi-déshydratées contenant un polymère muco-adhésif et un agent bioactif tel que, par exemple, une substance immunogène (comme un vaccin), cela permettant l'administration par voie orale ou nasale dudit agent bioactif essentiellement intact en direction de la surface d'une muqueuse chez l'animal et, en particulier, chez un animal aquatique.

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