C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/113 (2010.01) A61K 31/7088 (2006.01) C07H 21/02 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2563388
The invention relates to an isolated DNA or RNA pancreatic islet microRNA molecule. The invention further relates to a modified single stranded pancreatic islet microRNA molecule or an isolated single stranded anti- pancreatic islet microRNA molecule. The invention also provides for hod for inhibiting microRNP activity in a cell.
L'invention concerne une molécule isolée d'ADN ou d'ARN comprenant un micro-ARN d'îlot pancréatique. L'invention concerne également une molécule modifiée comprenant un micro-ARN d'îlot pancréatique à simple brin ou une molécule isolée comprenant un micro-ARN d'îlot anti-pancréatique à simple brin. L'invention concerne également une méthode permettant d'inhiber l'activité de microRNP dans une cellule.
Poy Matthew N.
Stoffel Markus
Tuschl Thomas H.
Smart & Biggar
The Rockefeller University
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