Microscale sensor element and related device and method of...

Details Microscale sensor element and related device and method of... Microscale sensor element and related device and method of...

H - Electricity

01

J

H01J 37/00 (2006.01) G01N 27/00 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2479861

A monitoring apparatus useful in detecting viability of biological cells (112). A substrate defines a microscopic chamber. One or more microcantilevers (106) extend from the substrate (102) into the chamber (104). A detector is operatively connected to the microcantilevers for sensing a state of deformation thereof. On each microcantilevers is deposited a layer of an environmentally sensitive hydrogel polymer having a configuration changing in accordance with presence of an environmental parameter.

L'invention concerne un appareil de contrôle utile pour détecter la viabilité de cellules biologiques. Un substrat délimite une chambre microscopique. Un ou plusieurs microcantilevers s'étendent du substrat et pénètrent dans la chambre. Un détecteur est relié de manière fonctionnelle aux microcantilevers pour détecter un état de déformation de ces derniers. Sur chaque microcantilever est déposée une couche de polymère d'hydrogel tenant compte de l'environnement, dont la configuration change selon qu'un paramètre écologique est présent.

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