Microsomal triglyceride transfer protein

Details Microsomal triglyceride transfer protein Microsomal triglyceride transfer protein

C - Chemistry, Metallurgy

12

N

C12N 15/61 (2006.01) A61K 31/495 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 3/06 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C12N 9/90 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2091102

Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention additionally concerns novel methods for lowering serum liquid levels and therapeutic agents having such activity.

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