A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 38/46 (2006.01)
Patent
CA 2428837
The present invention refers to new microspheres including pancreatic enzymes, pharmaceutical compositions containing them, and a process to obtain them. The process here described doesn't involve the use of solvents and proves to be remarkably shorter and efficient than the producing methods of the prior arts. The microspheres obtained, including one or more pancreatic enzymes, one or more hydrophilic low-melting polymers and eventual excipients, have an high enzymatic activity, bio-availability and stability.
La présente invention se rapporte à de nouvelles microsphères comportant des enzymes pancréatiques, à des compositions pharmaceutiques les contenant, et à un procédé permettant de les obtenir. Le procédé ci-décrit n'implique pas l'utilisation de solvants et s'avère nettement plus rapide et efficace que les procédés de production des techniques antérieures. Les microsphères obtenues, comportant une ou plusieurs enzymes pancréatiques, un ou plusieurs polymères hydrophiles à faible point de fusion et éventuellement des excipients, présentent une activité enzymatique, une biodisponibilité et une stabilité élevées.
Eurand International S.p.a.
Smart & Biggar
LandOfFree
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