Microspheroidal-controlled release of biomolecules

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/52 (2006.01) A61K 31/445 (2006.01) A61K 38/14 (2006.01) A61P 29/00 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2650503

Silica-based xerogel microspheres are provided containing pharmaceutically active compounds. These microspheres are robust, release active compounds at predictable rates and may provide such release for relatively long periods of time. Pharmaceutical compositions, methods for delivering medicaments and methods for treatment of disease states or conditions, inter alia, infection or pain, as well as methods for fabrication of such microspheres, are also provided.

La présente invention concerne des microsphères siliciées de xérogel contenant des composés pharmaceutiquement actifs. Ces microsphères sont robustes, libèrent des composés actifs à des débits prévisibles et peuvent accomplir cette libération sur des durées relativement importantes. La présente invention concerne en outre des compositions pharmaceutiques, des méthodes de libération de médicaments et des méthodes de traitement d'états pathologiques et de maladies, entre autres, d'infections ou de douleurs, ainsi que des méthodes de fabrication de telles microsphères.

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