Microstamping activated polymer surfaces

B - Operations – Transporting – 01 – J

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B01J 19/00 (2006.01) B05D 1/28 (2006.01) C07B 61/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/545 (2006.01) B05D 1/18 (2006.01)

Patent

CA 2400814

Functionalized polymer surfaces having reactive moieties thereon are contacted with stamps having ligands adsorbed thereto, the ligands also comprising reactive moieties. The reactive moieties of the functionalized surfaces and the ligands form covalent bonds, thus providing a method of microstamping polymer surfaces directly with ligands such as biological ligands. Using this method, devices such as tissue culture plates with polymer surfaces that are microstamped directly with ligands can be made.

Selon l'invention, des surfaces polymères fonctionnalisées comprenant des groupes fonctionnels réactifs sont mises en contact avec des estampes ayant absorbé des ligands, ces ligands comprenant également des groupes fonctionnels réactifs. Les groupes fonctionnels réactifs des surfaces fonctionnalisées et les ligands formant des liaisons covalentes autorisent un procédé de microestampage de surfaces polymères directement au moyen de ligands, tels que des ligands biologiques. Le procédé permet la réalisation de dispositifs tels que des plaques de culture de tissus à surfaces polymères étant microestampées directement avec des ligands.

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