Microwave-assisted peptide synthesis

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 1/10 (2006.01) C07K 1/04 (2006.01) C07K 1/08 (2006.01)

Patent

CA 2604609

An instrument and associated method are disclosed for the accelerated synthesis of peptides by the solid phase method. The instrument includes a microwave cavity, a microwave source in communication with the cavity, a column in the cavity formed of a material that is transparent to microwave radiation, a solid phase peptide support resin in the column, respective filters for maintaining the solid phase support resin in the column, a first passageway for adding starting compositions to the column, a second passageway for removing compositions from the column, and a third passageway for circulating compositions from the column into the third passageway and back to the column.

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