Microwave enhanced n-fmoc deprotection in peptide synthesis

Details Microwave enhanced n-fmoc deprotection in peptide synthesis Microwave enhanced n-fmoc deprotection in peptide synthesis

C - Chemistry, Metallurgy

07

K

C07K 1/06 (2006.01) C07K 1/04 (2006.01) C07K 1/10 (2006.01)

Patent

CA 2577650

A method is disclosed for carrying out peptide synthesis comprising deprotecting an Fmoc-protected amino acid with piperazine while applying microwave irradiation to the deprotection reaction.

On divulgue une méthode pour la synthèse d'un peptide par déprotection d'un acide aminé protégé par un groupement Fmoc à l'aide d'une pipérazine tout en soumettant le mélange réactionnel à un rayonnement micro-ondes pendant la réaction de déprotection.

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