C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/26 (2006.01) A61K 31/404 (2006.01) A61K 31/4184 (2006.01) A61K 31/423 (2006.01) A61K 31/428 (2006.01) A61L 31/16 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 209/34 (2006.01) C07D 263/58 (2006.01) C07D 277/68 (2006.01)
Patent
CA 2634212
The present invention relates to the use of specific benzimidazolone analogues and derivatives to inhibit the cytokine or biological activity of macrophage migration inhibitory factor (MIF), and diseases or conditions wherein MIF cytokine or biological activity is implicated. Novel benzimidazole analogues and derivatives are also provided.
La présente invention concerne l'utilisation d'analogues et de dérivés benzimidazolone spécifiques pour inhiber la cytokine ou une activité biologique du facteur inhibiteur de la migration des macrophages (MIF), et des maladies ou conditions dans lesquelles une cytokine ou une activité biologique MIF est impliquée. De nouveaux analogues et dérivés benzimidazole sont aussi obtenus.
Jozefiak Thomas H.
Li Xinhua
Morand Eric Francis
Skene Colin Edward
Tapley Peter Mark
Cortical Pty Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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