Migration of hematopoietic stem cells and progenitor cells...

Details Migration of hematopoietic stem cells and progenitor cells... Migration of hematopoietic stem cells and progenitor cells...

A - Human Necessities

61

K

A61K 38/19 (2006.01) C12N 5/0789 (2010.01) A61K 31/675 (2006.01) A61K 35/12 (2006.01) A61K 39/29 (2006.01) A61K 48/00 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2468944

The invention relates to transplantation of hematopoietic stem cells (HSC) and/or progenitor cells (HPC) into the liver. More specifically the invention relates to the use of chemokines, preferably SDF-1, for enhancing homing of HSC/HPC to the liver.

L'invention concerne la greffe de cellules souches hématopoïétiques (HSC) et/ou de cellules progénitrices hématopoïétiques (HPC) dans le foie. Elle concerne plus spécifiquement l'utilisation de chimiokines, de préférence SDF-1, pour améliorer la domiciliation de HSC/HPC dans le foie.

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