B - Operations – Transporting – 02 – C
Patent
B - Operations, Transporting
02
C
B02C 19/06 (2006.01) B02C 19/18 (2006.01)
Patent
CA 2352779
The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometers which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method comprises milling the material in a fluid energy mill at reduced temperature using helium, or helium mixed with another gas, as milling fluid. Temperatures of -30 ~C or less are used.
Cette invention a trait à un procédé de broyage de matières aux fins de la formation de fines d'une dimension particulaire moyenne inférieure à 10 micromètres, se prêtant bien à une inhalation et dont le broyage ne provoque quasiment pas de formation de contenu amorphe. Ce procédé, qui convient tout particulièrement au broyage de matières molles, consiste à broyer les matières dans un broyeur à tuyère à température réduite en utilisant de l'hélium ou de l'hélium mêlé à un autre gaz comme fluide de broyage. Les températures sont inférieures ou égales à 0 ·C.
Authelin Jean-Rene
Hosek Patrick
Aventis Pharma Limited
Ridout & Maybee Llp
LandOfFree
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