C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/08 (2006.01) A61K 38/06 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2599864
The invention relates to mimetic peptide compounds, to the synthesis and use thereof for inhibiting proteasomes and inducing apoptosis in tumoral cells. Pharmaceutical compositions containing said compounds and the use of said compounds for treating diseases, in particular cancer and neurogenerative diseases are also disclosed.
L'invention concerne des composés peptides mimétiques, leur synthèse et leur utilisation pour l'inhibition de protéasomes et l'induction de l'apoptose dans des cellules tumorales. L'invention concerne en outre des compositions pharmaceutiques comprenant lesdits composés, et l'utilisation de ces composés pour le traitement de maladies, en particulier des affections cancéreuses et des affections neurodégénératives.
Braun Hannes
Kloetzel Peter-Michael
Kuckelkorn Ulrike
Schmidt Boris
Umbreen Sumaira
Heenan Blaikie Llp
Technische Universitaet Darmstadt
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