C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/64 (2006.01) A61K 38/04 (2006.01) A61K 39/21 (2006.01) A61K 39/385 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/16 (2006.01) C12N 15/10 (2006.01) G01N 33/543 (2006.01) G01N 33/554 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2111681
2111681 9222579 PCTABS00018 Disclosed are peptides having a primary amino acid sequence which is unrelated to gp120. The peptides are characterized by the ability to stimulate the production of anti-gp120, particularly anti-V3-loop, antibodies when administered to a mammal. The peptides are also characterized by the ability to interfere with viral function. The peptides can be formulated as a vaccine composition and administered as a method for stimulating an HIV-1 neutralizing immune response.
Gefter Malcolm L.
Melmon Kenneth L.
Immulogic Pharmaceutical Corporation
Smart & Biggar
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