Mimotopes of hiv env

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/16 (2006.01) A61K 39/21 (2006.01) A61K 39/385 (2006.01) A61K 39/42 (2006.01) A61P 31/18 (2006.01) A61P 37/04 (2006.01) C07K 16/10 (2006.01) C12N 5/16 (2006.01) C12N 15/49 (2006.01)

Patent

CA 2739905

The invention provides methods, compositions and kits for treating and or preventing an HIV infection. For exam-ple, HIV envelope-like polypeptides (wild- type HIV polypeptides and mimotopes) may be administered to an individual so as to induce a protective immune response to HIV. Alternatively, antibodies directed to the HIV envelope-like polypeptides may be ad-ministered to an individual to treat or prevent an HIV infection and/or one or more symptoms associated with the infection (e.g.,AIDS).

La présente invention concerne des procédés, des compositions et des trousses pour traiter et ou prévenir une infection par le VIH. Par exemple, des polypeptides de type denveloppe de VIH (polypeptides de VIH de type sauvage et mimotopes) peuvent être administrés à un individu de manière à induire une réponse immunitaire protectrice au VIH. En variante, des anticorps dirigés contre les polypeptides de type enveloppe de VIH peuvent être administrés à un individu pour traiter ou prévenir une infection par le VIH et/ou un ou plusieurs symptômes associés à linfection (par exemple,le SIDA).

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