Minrs as modifiers of insulin receptor signaling and methods...

Details Minrs as modifiers of insulin receptor signaling and methods... Minrs as modifiers of insulin receptor signaling and methods...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2473499

Human MINR genes are identified as modulators of INR signaling and thus are therapeutic targets for disorders associated with defective INR signaling. Methods for identifying modulators of MINR, comprising screening for agents that modulate the activity of MINR are provided.

Selon cette invention, des gènes MINR humains sont identifiés en tant que modulateurs de signalisation par les récepteurs de l'insuline et constituent, ainsi, des cibles thérapeutiques dans le traitement de troubles associés à une signalisation par les récepteurs de l'insuline défectueuse. Cette invention concerne également des procédés d'identification de modulateurs de signalisation par les récepteurs de l'insuline, consistant à sélectionner des agents modulant l'activité de signalisation par les récepteurs de l'insuline.

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