C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2597767
The invention provides methods for diagnosing B-cell lymphoma in an animal. In particular, the invention provides methods for distinguishing an animal having diffuse large B-cell lymphoma (DLBCL) with an activated B-cell (ABC) phenotype from an animal having DLBCL with a non-activated germinal-center (GC) phenotype. The invention also provides methods for identifying compounds for treating B-cell lymphoma. The invention further provides reagents and methods for determining the amount of miR-155 in sample isolated from an animal. In this regard, the invention provides a set of oligonucleotides for determining the amount of miR-155 in sample isolated from an animal.
L'invention concerne des méthodes de diagnostic du lymphome B chez un animal, en particulier des méthodes permettant de distinguer un animal souffrant d'un lymphome B diffus à grandes cellules avec phénotype de cellules B acitvé d'un autre animal avec DLBCL et phénotype à centre germinatif non activé. L'invention concerne également des méthodes d'identification de composés utiles pour le traitement du lymphome B. Elle porte en outre sur des réactifs et des méthodes permettant de déterminer la quantité de miR-155 dans un échantillon prélevé sur un animal, ceci au moyen d'un ensemble d'oligonucléotides.
Dahlberg James
Eis Peggy
Lund Elsebet
Tam Wayne
Borden Ladner Gervais Llp
Cornell Research Foundation Inc.
Wisconsin Alumni Research Foundation
LandOfFree
Mir-155 assay does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mir-155 assay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mir-155 assay will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1868491