Mitochondrial membrane stabilizer

Details Mitochondrial membrane stabilizer Mitochondrial membrane stabilizer

A - Human Necessities

61

K

A61K 31/505 (2006.01) A61K 31/40 (2006.01) A61K 31/4015 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/47 (2006.01) A61K 31/472 (2006.01) A61K 31/519 (2006.01) C07D 207/27 (2006.01)

Patent

CA 2267375

A preventive and/or remedy for diseases caused by or accompanied with mitochondrial function anomalies, such as ischemic diseases, toxicosis and degenerative diseases, containing as the active ingredient a substance exhibiting the effect of stabilizing mitochondria by stabilizing the membrane potential thereof, such as 2,6-dimethylanilide of 2-oxo-1-pyrrolidinylacetic acid functioning as a benzodiazepine receptor antagonist.

L'invention concerne un agent préventif et/ou curatif pour les maladies provoquées par ou accompagnées d'anomalies de la fonction mitochondriale, telles que les affections ischémiques, la toxicose et les affections dégénératives, contenant comme principe actif, une substance ayant pour effet de stabiliser la mitochondrie en stabilisant le potentiel de membrane de celle-ci, telle que la 2,6-diméthylanilide d'acide 2-oxo-1-pyrrolidinylacétique fonctionnant comme un antagoniste du récepteur de la benzodiazépine.

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