Mitochondrial mutations and rearrangements as a diagnostic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/53 (2006.01) A61P 35/00 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) C40B 40/08 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2606156

Mitochondrial DNA deletions useful for the detection of cancers and sun exposure are provided. In particular, methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melonoma skin cancer are provided.

Les délétions d'ADN mitochondriales sont utiles pour la détection des cancers et de l'exposition au soleil. L'invention porte notamment sur des méthodes et des kits de détection de délétions d'ADN mitochondriales pour la détection précoce et le diagnostic, de la progression du cancer de la prostate, de l'exposition au soleil et du cancer de la peau non mélanique.

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