Mitochondrially targeted antioxidants

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 13/00 (2006.01) A61K 31/555 (2006.01) C07D 293/12 (2006.01) C07F 9/547 (2006.01) C07F 9/58 (2006.01) C07F 9/6539 (2006.01) C07F 11/00 (2006.01) C09K 15/00 (2006.01)

Patent

CA 2397684

The invention provides mitochondrially targeted antioxidant compounds comprising a lipophilic cation moiety covalently coupled to an antioxidant moiety which is either a superoxide dismutase (SOD) mimetic or a glutathione peroxidase mimetic. These compounds can be used to treat patients who would benefit from the reduction of oxidative stress.

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