Mitochondrially targeted antioxidants

Details Mitochondrially targeted antioxidants Mitochondrially targeted antioxidants

C - Chemistry, Metallurgy

07

F

C07F 9/54 (2006.01) A61K 31/66 (2006.01) C07D 293/12 (2006.01)

Patent

CA 2494173

The invention provides mitochondrially targeted antioxidant compounds comprising a lipophilic cation moiety covalently coupled to a glutathione peroxidase mimetic. These compounds can be used to treat patients who would benefit from the reduction of oxidative stress.

L'invention concerne des composés antioxydants ciblés pour agir sur les mitochondries, comprenant une fraction cationique lipophile couplée de manière covalente à un mimétique de la glutathione peroxydase. Lesdits composés peuvent être utilisés pour traiter des patients qui pourraient bénéficier de la réduction du stress oxydatif.

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