Mitotic inhibitor and method for preventing posterior lens...

Details Mitotic inhibitor and method for preventing posterior lens... Mitotic inhibitor and method for preventing posterior lens...

A - Human Necessities

61

K

167/129

A61K 39/395 (2006.01) A61F 2/00 (2006.01) A61F 2/16 (2006.01) A61K 47/48 (2006.01) A61L 27/54 (2006.01)

Patent

CA 1339770

MITOTIC INHIBITOR AND METHOD FOR PREVENTING POSTERIOR LENS CAPSULE OPACIFICATION AFTER EXTRACAPSULAR EXTRACTION A conjugated cytotoxin is provided for preventing posterior lens capsule opacification (after-cataract) after extracapsular extraction. Preferably, the mitotic inhibitor of lens epithelial cells comprises a conjugate containing methotrexate which is covalently linked to an antibody, such as anticollagen, in approximately a molar ratio of 1:1 to 10:1. The mitotic conjugate may be instilled in the anterior or posterior chamber of the eye, preferably immediately after the lens has been removed, or coated onto an intraocular lens prior to insertion onto the posterior lens capsule. Similar conjugates may be attached to other artificial materials in the body to fight fibroblast proliferation.

572099

Affiliated with

Also associated with

Rating

Mitotic inhibitor and method for preventing posterior lens... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mitotic inhibitor and method for preventing posterior lens..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mitotic inhibitor and method for preventing posterior lens... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1249238