Mitotic kinesin binding site

Details Mitotic kinesin binding site Mitotic kinesin binding site

C - Chemistry, Metallurgy

12

N

C12N 9/00 (2006.01) C07K 17/00 (2006.01) C12N 9/14 (2006.01) C12Q 1/00 (2006.01) C12Q 1/34 (2006.01) G01N 33/68 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2489562

The present invention is directed to the identification, characterization and three-dimensional structure of a novel ligand binding site of KSP. Binding of ligands to the novel binding site result in a conformational change in the three-dimensional structure of the protein and a modulation of the activity of KSP. This conformational change in turn results in the formation of a novel binding pocket in the KSP protein, which comprises the novel binding site of the instant invention.

L'invention concerne l'identification, la caract~risation et la structure tridimensionnelle d'un site de liaison de ligand de KSP. La liaison de ligands ~ ce site de liaison r~sulte en une modification conformationnelle de la structure tridimensionnelle de la prot~ine et en une modulation de l'activit~ de KSP. Cette modification conformationnelle permet parfois de former une poche de liaison dans la prot~ine KSP, qui comprend le site de liaison de cette invention.

Affiliated with

Also associated with

Rating

Mitotic kinesin binding site does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mitotic kinesin binding site, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mitotic kinesin binding site will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2016040