C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/513 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 239/36 (2006.01)
Patent
CA 2561904
The present invention relates to compounds that are useful for treating cellular proliferative diseases, for treating disorders mediated, at least in part, by KSP, and for inhibiting KSP. The invention also related to pharmaceutical compositions comprising such compounds, methods of treating cancer by the administration of such compositions, and processes for the preparation of the compounds. Compounds of the invention have the following formula : formula (I).
L'invention concerne des composés utiles pour le traitement de maladies à prolifération cellulaire, pour le traitement de troubles médiés, au moins en partie, par KSP, et pour l'inhibition de KSP. L'invention porte également sur des compositions pharmaceutiques comprenant lesdits composés, sur des méthodes de traitement du cancer par l'administration desdites compositions et sur des procédés de préparation desdits composés. Les composés de l'invention sont représentés par la formule (I).
Constantine Ryan
Lagniton Liana
Wang Weibo
Borden Ladner Gervais Llp
Chiron Corporation
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