C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/02 (2006.01) C07D 207/20 (2006.01) C07D 207/263 (2006.01) C07D 295/02 (2006.01)
Patent
CA 2486215
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
La présente invention concerne des composés de dihydropyrazole utiles pour traiter les troubles associés à l'activité de kinésine KSP et pour inhiber la kinésine KSP. L'invention concerne aussi des compositions qui comprennent ces composés et des procédés pour les utiliser dans le traitement du cancer affectant les mammifères.
Arrington Kenneth L.
Fraley Mark E.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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