Mitotic kinesin inhibitors and methods of use thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/04 (2006.01) A61K 31/433 (2006.01) A61K 31/437 (2006.01) C07D 285/12 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2606708

This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.

L'invention concerne des inhibiteurs de kinésine mitotique, en particulier KSP, et des méthodes pour produire ces inhibiteurs. L'invention concerne des compositions pharmaceutiques comprenant les inhibiteurs de l'invention, et des méthodes d'utilisation de ces inhibiteurs et de ces compositions pharmaceutiques pour traiter et pour prévenir des troubles variés.

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