Mitotic kinesin inhibitors and methods of use thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 285/12 (2006.01) A61K 31/4245 (2006.01) A61K 31/433 (2006.01) A61K 31/4439 (2006.01) C07D 271/10 (2006.01) C07D 401/12 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2584866

This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.

L'invention concerne des inhibiteurs des kinésines mitotiques, notamment du type KSP, et des méthodes permettant de produire ces inhibiteurs. L'invention concerne également des compositions pharmaceutiques comprenant ces inhibiteurs ainsi que des méthodes d'utilisation de ces inhibiteurs et de ces compositions pharmaceutiques dans le traitement et la prévention de divers troubles.

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