Mixed lipopeptide micelles for inducing an immune response

Details Mixed lipopeptide micelles for inducing an immune response Mixed lipopeptide micelles for inducing an immune response

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 9/107 (2006.01) A61K 38/17 (2006.01) A61K 39/015 (2006.01) A61K 39/215 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2312043

The invention concerns mixed micelles or micro-aggregates for inducing an immune response containing at least: a first lipopeptide comprising a CTL epitope and at least a first lipid motif; and a second lipopeptide comprising at least an auxiliary T epitope and at least a lipid motif, whereof the type can be different from the first lipopeptide motif. Said micelles can be used as medicines and vaccines.

Micelles mixtes ou micro-agrégats pour l'induction d'une réponse immunitaire contenant au moins: un premier lipopeptide comprenant au moins un épitope CTL et au moins un motif lipidique, et un second lipopeptide comprenant au moins un épitope T auxiliaire et au moins un motif lipidique, dont la nature peut être différente du motif du premier lipopeptide. Ces micelles peuvent être utilisées dans des médicaments et vaccins.

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