Mixed salts of essential or semi-essential amino acids and...

Details Mixed salts of essential or semi-essential amino acids and... Mixed salts of essential or semi-essential amino acids and...

C - Chemistry, Metallurgy

07

D

260/314, 260/516

C07D 233/64 (2006.01) A61K 31/195 (2006.01) C07D 209/20 (2006.01) C07D 233/54 (2006.01)

Patent

CA 1139768

Abstract of the Disclosure Novel compounds are prepared by reacting essential or semi-essential amino acids with nitrogen-free analogues thereof, particularly alpha-keto and/or alpha-hydroxy analogues. The mixed salt reaction products are precursors of essential and semi-essential amino acids in the body, and mixtures of the salts are useful in the treatment of renal and hepatic disorders characterized by protein intolerance leading to deficiencies of various essential and semi-essential amino acids in the body. They may also be useful in the treatment of nitrogen wasting disorders and protein malnutrition. The novel compounds are generally far more palatable and soluble in aqueous solution than the individual essential or semi-essential amino acids, nitrogen-free analogues thereof, or sample mixtures of these.

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