A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01) C07K 14/475 (2006.01)
Patent
CA 2506855
The present invention is directed to novel peptides and compositions capable of modulating viability and growth in neuronal cells, and to methods of modulating neuronal cell viability and growth employing the novel peptides and compositions of the invention. In one aspect, the invention is directed to novel peptide analogues of motoneuronotrophic factor 1 containing either a ~WMLSAFS~ or ~FSRYAR domain,~ which is sufficient for neurotrophic or neurotropic function.
La présente invention a trait à de nouveaux peptides et compositions capables de moduler la viabilité et la croissance dans des cellules nerveuses, et à des procédés de modulation de la viabilité et de la croissance des cellules nerveuses utilisant les nouveaux peptides et compositions de l'invention. Dans un mode de réalisation, l'invention a trait à de nouveaux analogues peptidiques de facteur trophique de motoneurone 1 (MNTF 1) contenant soit un domaine WMLSAFS ou FSRYAR , qui est suffisant pour une fonction neurotrophique ou neurotropique.
Chau Raymond Ming Wah
Ko Tiu-Yak Dorothy
Genervon Biopharmaceuticals Llc
Gowling Lafleur Henderson Llp
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