Model and method for inhibiting angiogenesis using...

Details Model and method for inhibiting angiogenesis using... Model and method for inhibiting angiogenesis using...

A - Human Necessities

61

K

A61K 41/00 (2006.01)

Patent

CA 2346643

The invention provides a method to inhibit the formation of neovasculature while maintaining viability of the underlying tissue by subjecting a subject in which angiogenesis is to be inhibited to sublethal photodynamic therapy. The invention also provides a model for assessing sublethal PDT protocols to inhibit angiogenesis in particular target tissues.

L'invention concerne un procédé d'inhibition de la néovascularisation et de maintien simultané de la viabilité du tissu sous-jacent. Ladite méthode consiste à soumettre à une thérapie photodynamique sublétale un sujet chez lequel l'angiogenèse doit être inhibée. L'invention se rapporte également à un modèle pour l'évaluation de protocoles de thérapie photodynamique sublétale, destinés à inhiber l'angiogenèse dans des tissus cibles particuliers.

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