Modification of biopolymers for improved drug delivery

Details Modification of biopolymers for improved drug delivery Modification of biopolymers for improved drug delivery

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2400205

A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a suitable carrier, has improved in vivo stability and activity, and can be targeted to a variety of cells, tissues and organs.

L'invention concerne un conjugué biologiquement actif, qui contient un biopolymère et un agent thérapeutique réunis par une liaison disulfure. Le conjugué, formulé en une composition pharmaceutique avec un excipient approprié, possède une stabilité et une activité in vivo accrues et peut être ciblé sur diverses cellules, divers tissus et organes.

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