Modifications of hiv env, gag, and pol enhance...

Details Modifications of hiv env, gag, and pol enhance... Modifications of hiv env, gag, and pol enhance...

C - Chemistry, Metallurgy

12

N

C12N 15/49 (2006.01) A61K 39/21 (2006.01) C07K 14/16 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2419822

Modified HIV Env, Gag, Pol, or Nef DNA with improved ability to elicit antibody and CTL responses to HIV antigens have been identified as prototype immunogens for the treatment and prevention of HIV infections.

L'invention concerne des ADN modifiés Env, Gag, Pol, ou Nef de VIH, présentant un pouvoir amélioré de provocation de réponses d'anticorps et de cellules T cytotoxiques contre des antigènes de VIH, et qui ont été identifiés en tant qu'immunogènes prototypes pour le traitement et la prévention d'infections par le VIH.

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