Modified 4'-nucleosides as antiviral agents

C - Chemistry – Metallurgy – 12 – P

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C12P 19/38 (2006.01) C12P 19/30 (2006.01) C12P 19/40 (2006.01)

Patent

CA 2623522

Compounds, methods and compositions for treating a host infected with human immunodeficiency virus and hepatitis B virus comprising administering an effective amount of a described 4'-C-substituted /3-D- and /3-L-nucleoside or a pharmaceutically acceptable salt or prodrug thereof, are provided.

L'invention porte sur des composés, sur des méthodes et sur des compositions de traitement d'un hôte infecté par le virus de l'immunodéficience humaine et le virus de l'hépatite B, ces méthodes consistant à administrer une quantité effective d'un 4'-C-substitué ß-D et ß-L-nucléoside de l'invention ou d'un sel acceptable d'un point de vue pharmaceutique ou d'un promédicament de celui-ci.

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