Modified adenoviral fibre and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/861 (2006.01) A61K 48/00 (2006.01) C07K 14/075 (2006.01) C12N 5/10 (2006.01) C12N 15/34 (2006.01)

Patent

CA 2348158

The invention concerns a modified adenoviral fibre comprising at least one mutation at the level of one or several residues included in the region of said fibre extending from layer A to layer B and including the loop AB.

La présente invention a pour objet une fibre d'un adénovirus modifée comprenant au moins une mutation au niveau d'un ou plusieurs résidus compris dans la région de ladite fibre s'étendant du feuillet A au feuillet B et incluant la boucle AB.

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