Modified amino acids for drug delivery

Details Modified amino acids for drug delivery Modified amino acids for drug delivery

C - Chemistry, Metallurgy

07

C

C07C 233/63 (2006.01) A61K 9/16 (2006.01) A61K 31/16 (2006.01) A61K 31/352 (2006.01) A61K 31/727 (2006.01) A61K 38/21 (2006.01) A61K 38/23 (2006.01) A61K 47/16 (2006.01) A61K 47/18 (2006.01) C07C 229/42 (2006.01) C07C 233/48 (2006.01) C07C 233/55 (2006.01) C07C 233/87 (2006.01) C07C 235/38 (2006.01) C07C 235/64 (2006.01) C07C 235/84 (2006.01) C07C 237/22 (2006.01) C07C 275/42 (2006.01) C07C 279/14 (2006.01) C07D 209/20 (2006.01) C07K 1/107 (2006.01) C07K 5/06 (2006.01) C07K 5/072 (2006.01) A61K 38/00 (2006.

Patent

CA 2188467

The present invention relates to an oral delivery system, and in particular to modified amino acids or peptides for use as a delivery system of sensitive agents such as bioactive peptides. The modified amino acids or peptides can form non-covalent mixtures or microspheres with active biological agents. These mixtures or microspheres are suitable for oral administration of biologically active agents to animals. Methods for the preparation of such amino acids and peptides are also disclosed.

Système d'administration orale, et en particulier acides aminés ou peptides modifiés destinés à être utilisés comme système d'administration d'agents sensibles tels que des peptides bioactifs. Lesdits acides aminés et peptides modifiés peuvent former des mélanges non covalents ou des microsphères avec des agents biologiques actifs. Ces mélanges ou microsphères conviennent pour l'administration orale d'agents biologiquement actifs à des animaux. Des procédés de préparation d'acides aminés et peptides de la présente invention sont également décrits.

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