C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/02 (2006.01) A61P 37/00 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2544365
The present invention provides for modified forms of anti-CD52 antibodies with reduced numbers of potential T-cell epitopes that are expected to display decreased immunogenicity.
L'invention concerne des formes modifiées d'anticorps anti-CD52 qui ont un nombre réduit d'épitopes potentiels de lymphocytes T et qui sont censés présenter une immunogénicité diminuée.
Carr Francis J.
Hamilton Anita A.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biovation Ltd.
Merck Patent Gmbh
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