Modified asialo-interferons and uses thereof

Details Modified asialo-interferons and uses thereof Modified asialo-interferons and uses thereof

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 38/21 (2006.01)

Patent

CA 2497777

The present invention features methods for preparing and using modified asialo- interferons for the treatment of hepatic diseases. Asialo-interferons are modified by the addition of water soluble polymers including, for example, polyethylene glycol (PEG), polyvinylpyrrolidone (PVP), poly(vinyl alcohol) (PVA), poly (alkylene oxides), such as poly (propylene glycol) (PPG), polytrimethylene glycol (PTG), and poly(oxyethylated polyols), such as poly(oxyethylated sorbitol), poly(oxyethylated glycerol, and poly(oxyethylated glucose). The asialo-interferons that may be modified and used for the treatment of hepatic diseases include, for example, asialo-interferon-a, -R, and -y.

Cette invention se rapporte à des procédés pour préparer et utiliser des asialo-interférons modifiés dans le traitement des maladies hépatiques. Ces asialo-interférons sont modifiés par l'addition de polymères hydrosolubles, tels que notamment du polyéthylène-glycol (PEG), du polyvinylpyrrolidone (PVP), du poly(alcool de vinyle) (PVA), des poly(oxydes d'alkylène), tel que du poly(glycol de propylène) (PPG), du polytriméthylène-glycol (PTG), et des poly(polyols oxyéthylés), tel que du poly(sorbitol oxyéthylé), du poly(glycérol oxyéthylé), et du poly(glucose oxyéthylé). Ces asialo-interférons qui peuvent être modifiés et utilisés pour le traitement des maladies hépatiques sont notamment l'asialo-interféron .alpha., .beta., et .gamma..

Affiliated with

Also associated with

Rating

Modified asialo-interferons and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Modified asialo-interferons and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modified asialo-interferons and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1791352