C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/235 (2006.01) A61K 39/10 (2006.01) A61P 11/00 (2006.01) A61P 31/00 (2006.01) C12N 9/88 (2006.01) C12N 15/60 (2006.01)
Patent
CA 2529565
The invention relates to modified Bordetella adenylate cyclase toxins which are deficient for CD11b/CD18 binding and to their use in the preparation of pharmaceutical composition for the treatment of whooping cough and/or for the protection against Bordetella infection. The invention also relates to specific fragments of Bordetella adenylate cyclase comprising the CD11b/CD18 interaction domain and their use, especially for targeting a molecule of interest to CD11b expressing cells.
L'invention a trait à des toxines d'adénylate cyclase Bordetella modifiée qui présentent une liaison déficiente CD11b/CD18 et à leur utilisation dans la préparation d'une composition pharmaceutique pour traiter la coqueluche et/ou prévenir une infection à Bordetella. L'invention se réfère également à des fragments spécifiques d'adénylate cyclase Bordetella comprenant le domaine d'interaction CD11b/CD18 et à leur utilisation, notamment pour cibler une molécule voulue sur des cellules exprimant CD11b.
Bauche Cecile
El-Azami El-Idrissi Mohammed
Ladant Daniel
Leclerc Claude
Loucka Jirina
Centre National de La Recherche Scientifique
Institut Pasteur
Robic
LandOfFree
Modified bordetella adenylate cyclase comprising or lacking... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Modified bordetella adenylate cyclase comprising or lacking..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modified bordetella adenylate cyclase comprising or lacking... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1466214