C - Chemistry – Metallurgy – 09 – B
Patent
C - Chemistry, Metallurgy
09
B
C09B 23/02 (2006.01) C07C 66/02 (2006.01) C07D 209/08 (2006.01) C07D 209/12 (2006.01) C07D 209/14 (2006.01) C07D 209/16 (2006.01) C07D 209/18 (2006.01) C07D 209/24 (2006.01) C07D 209/54 (2006.01) C07D 209/60 (2006.01) C07D 403/14 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01) C12Q 1/68 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2423806
Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens.
L'invention concerne des colorants carbocyanines chimiquement réactifs contenant un fragment cyclique d'indolium qui est substitué au niveau de la position 3 par un groupe réactif ou une substance conjuguée, et leurs utilisations. La conjugaison à travers cette position résulte en des propriétés spectrales uniformément supérieures à celles des conjugués de colorants similaires sur le plan spectral dans lesquels l'attache s'effectue au niveau d'une position différente. L'invention concerne également des composés dérivés possédant un ou plusieurs benzoazotes.
Cheung Ching-Ying
Leung Wai-Yee
Yue Stephen
Mbm Intellectual Property Law Llp
Molecular Probes Inc.
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