A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/275 (2006.01) A61F 2/28 (2006.01) A61F 2/44 (2006.01) A61F 2/46 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01) A61B 17/28 (2006.01) A61F 2/00 (2006.01) A61F 2/30 (2006.01)
Patent
CA 2481719
The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and / or treating cancer. The invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. One such foreign DNA sequence is modified CEA nucleic acid.
L'invention concerne des acides nucléiques codant un polypeptide et l'utilisation de cet acide nucléique ou polypeptide dans la prévention et/ou le traitement du cancer. L'invention se rapporte à des vecteurs améliorés permettant l'insertion et l'expression de gènes étrangers codant des antigènes d'une tumeur utilisés dans un traitement immunothérapeutique du cancer. Cette séquence d'ADN étrangère est un acide nucléique d'antigène carcinoembryonnaire (CEA) modifié.
Greenhalgh Trish
Gritz Linda R.
Parrington Mark
Rovinski Beni
Zhang Linong
Aventis Pasteur Limited
Sanofi Pasteur Limited
Therion Biologics Inc.
Yacoob Reza K.
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